Basic Guide: Laboratory Testing

What is a PCR test?

PCR (or polymerase chain reaction) is a laboratory method for detecting the genetic material of an infectious disease agent in specimens from patients. This type of testing has become an essential tool for detecting infectious disease agents.

What does serologic testing involve?

A serologic test is a laboratory method for detecting the presence and/or level of antibodies to an infectious agent in serum from a person. Antibodies are substances made by the body's immune system to fight a specific infection.

What does viral culture and isolation involve?

For a viral culture, a small sample of tissue or fluid that may be infected is placed in a container along with cells in which the virus can grow. If the virus grows in the culture, it will cause changes in the cells that can be seen under a microscope.

Interactive

• SARS Quiz
  In this quiz you will find questions based on the information available in Basic Guide, Virus and Prevention.
  
  
• Crossword puzzle 1: Basic Guide
  Online crossword puzzle based on Basic Guide.
  
  
• SARS Quest - Averting An Outbreak
  In this short Flash game, you will be taking on the role of the Health Minister of the imaginary country of Asitwon. Your aim is to use all necessary means to prevent a SARS outbreak in the country.

Related Links

• RT-PCR Testing at the Laboratory Response Network
  More information about RT-PCR testing with SARS from the CDC (Centers for Disease Control and Prevention).

References

• Basic Information About SARS. (2004, January 13). Retrieved 2004 from CDC:
  http://www.cdc.gov/ncidod/sars/factsheet.htm
  
  
• Frequently Asked Questions About SARS. (2004, January 28). Retrieved 2004 from CDC:
  http://www.cdc.gov/ncidod/sars/faq.htm
  
  
• Chinese Student & Scholar Association, UK. (2003). Retrieved 2003 from: http://www.cssauk.org.uk/news/2003-04-29-pictures.htm

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